Causal association of type 1 diabetes with pancreatic cancer: a multi-ancestry Mendelian randomization study.

Given the marginally significant results and the limited number of IV SNPs, our East Asian estimate is purely hypothesis-generating and should not be considered conclusive evidence of a causal relationship.

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Discussion Using multi-ethnic large-sample GWAS data and MR analysis methods, we found a marginally statistically significant association between genetically predicted T1D and PCa in East Asians, which should be interpreted cautiously due to the limited number of instrumental SNPs and relatively small sample size.

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