Barely Significant
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Global, regional, and national burden of bone and joint infections, 1990-2021: a comprehensive analysis of trends, pathogens, and antimicrobial resistance.

Front Cell Infect Microbiol · 2026 · PMC13269380 · PMID 42312036

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an increasing trendno p-value reported
3.2 Regional discrepancies From 1990 to 2021, all regions experienced an increasing trend in the ASMR and ASDR for BJIs, with East Asia exhibiting the most pronounced increase.

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