Tests were done by Graph Pad Prism® software package version 9 (GraphPad Software Inc., CA, USA), and the differences were considered at p < 0.05, p < 0.01, p < 0.001, and p < 0.0001, corresponding to significant, highly significant, very highly significant and extremely significant, respectively.
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Amino acids protect against methotrexate-induced hepatorenal toxicity in vitro and in vivo.
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