Neural Circuit Mechanisms of General Anaesthesia Induction: Current Advances and Future Directions.

Curr Neuropharmacol · 2026 · PMC13269950 · PMID 40999609

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Studies in Sprague-Dawley rats suggest that orexinergic neurons may be significant targets for ketamine, with orexin A (OXA) neurons reducing the duration of ketamine-induced anesthesia [ 110 ].

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