Barely Significant
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Global Burden of Early-Onset Gastrointestinal Cancers Among Core Labor Force From 1990 to 2021: Insights From the Global Burden of Disease Study 2021.

Cancer Control · 2026 · PMC13269990 · PMID 42290017

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a decreasing trendno p-value reported
Conversely, if the estimates and the upper boundary of the 95% CI were both below 0, a decreasing trend was considered to be present.

also in 47,180 other papers

an increasing trendno p-value reported
When both the APC/AAPC estimates and the lower boundary of the 95% CI were above 0, an increasing trend was considered to be present during a specific period.

also in 63,971 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.