Genetic variation at the IL-18-137C>G is associated with poor sepsis prognosis and enhanced inflammatory responses: a multicenter hospital-based study.

Front Genet · 2026 · PMC13271677 · PMID 42311758

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borderline significanceno p-value reported

Additionally, although the IL-18 rs187238 polymorphism is associated with sepsis prognosis, its modest effect size and borderline significance suggest that further research is needed to confirm its clinical relevance as a reliable prognostic marker.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.

Genetic variation at the IL-18-137C&gt;G is associated with poor sepsis prognosis and enhanced inflammatory responses: a multicenter hospital-based study.

The sentences

Genetic variation at the IL-18-137C>G is associated with poor sepsis prognosis and enhanced inflammatory responses: a multicenter hospital-based study.