Pathway information on methylation analysis using deep neural network (PROMINENT): An interpretable deep learning method with pathway prior for phenotype prediction using gene-level DNA methylation.

Artif Intell Med · 2025 · PMC13273382 · PMID 40972407

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may be significantno p-value reported

First, the method aggregates CpG-level DNA methylation data at the gene level, enhancing computational efficiency by reducing dimensionality; however, it fails to identify critical CpG sites that may be significant on their own.

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