Extracellular vesicles inherit lactate from aggregated MSCs to alleviate type 1 diabetes mellitus via H<sub>2</sub>S-induced CD8<sup>+</sup> T cell exhaustion.

J Nanobiotechnology · 2026 · PMC13274048 · PMID 42050682

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not as significantno p-value reported

In contrast, the T1DM groups exhibited persistent severe lesions and the recovery of the adherent MSC EV treatment group was not as significant as that of the agg-EV treatment group (Fig. 3 B).

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Extracellular vesicles inherit lactate from aggregated MSCs to alleviate type 1 diabetes mellitus via H&lt;sub&gt;2&lt;/sub&gt;S-induced CD8&lt;sup&gt;+&lt;/sup&gt; T cell exhaustion.

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Extracellular vesicles inherit lactate from aggregated MSCs to alleviate type 1 diabetes mellitus via H<sub>2</sub>S-induced CD8<sup>+</sup> T cell exhaustion.