Barely Significant
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Clinical Analysis of Rotational-Translational Error Coupling in 3DoF Versus 6DoF CBCT Couch Corrections:A Cross-Sectional Study.

Technol Cancer Res Treat · 2026 · PMC13276233 · PMID 42305096

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highly significantno p-value reported
Quantitative analysis demonstrated a highly significant negative correlation between rotational and translational errors in NPC (Pitch vs. ΔVrt, r = −0.893), which lends robust support to the “lever-arm effect” hypothesis proposed by Gutfeld et al. 25 Consistent with the findings of Graff P et al in head and neck radiotherapy, 26 the data suggests that rigid-body registration algorithms may misinterpret rotations as translational shifts when the anatomical center of rotation deviates from the treatment isocenter.

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