Venous Thromboembolism Risk in Transgender Women on Feminizing Hormone Therapy: A Narrative Review of Formulation-Specific Risks, Management Strategies, and Evidence Gaps.

Cureus · 2026 · PMC13280713 · PMID 42328257

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a nonsignificant trendno p-value reported

In another observational study of postmenopausal women using HRT, oral CEE use was associated with a significantly higher risk of VTE (OR 2.08, P = .045) than E2, with a nonsignificant trend toward increased myocardial infarction and no difference in ischemic stroke risk [ 22 ].

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