Burden and Trends of Six Gynecological Diseases Among Chinese Women Aged 15-49 Years, 1990-2021: Evidence from GBD 2021.

3 The burden of polycystic ovary syndrome (PCOS) in China has exhibited an increasing trend over time, with a rate of increase surpassing the global average. 4 In 2022, the number of new cases of uterine corpus cancer in China was 50,100, while that of ovarian cancer was 39,100. 5 The age-standardized incidence and prevalence of endometriosis in China have remained consistently higher than the global averages over the long term. 6 In addition, studies have shown that the burden of gynecological diseases has increased alongside delayed childbearing, population aging, and lifestyle transitions, posing substantial challenges to women’s reproductive health and healthcare systems.

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The 95% CI of the EAPC was used to determine the statistical significance of the trend: an EAPC > 0 (with its 95% CI excluding zero) indicates an increasing trend, whereas an EAPC < 0 indicates a decreasing trend. 8 A trend was considered not statistically significant if the 95% CI included zero.

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