Pharmacological ZO-1 agonist treatment attenuates ammonia nitrogen stress-induced mucosal inflammation and intestinal barrier failure in <i>Leiocassis longirostris</i>.

Front Immunol · 2026 · PMC13284113 · PMID 42338597

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a decreasing trendno p-value reported

Although the changes in glud1 and glul expression were not statistically significant but showed a decreasing trend, suggesting partial amelioration of the nitrogen metabolism disorder by the ZO-1 agonist. 3.4 The ZO-1 agonist is associated with preservation of TJ protein complex organization GSEA ( Figures 5A–C ) revealed that the TJ pathway (KO04530) was significantly upregulated in the Control vs.

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Pharmacological ZO-1 agonist treatment attenuates ammonia nitrogen stress-induced mucosal inflammation and intestinal barrier failure in &lt;i&gt;Leiocassis longirostris&lt;/i&gt;.

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Pharmacological ZO-1 agonist treatment attenuates ammonia nitrogen stress-induced mucosal inflammation and intestinal barrier failure in <i>Leiocassis longirostris</i>.