Barely Significant
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Alterations of sphingosine-1-phosphate and its receptors in type 1 diabetes mellitus: an integrated clinical and single-cell transcriptomic study.

Front Immunol · 2026 · PMC13284128 · PMID 42338584

Europe PMCDOI
1
hedged sentence
0.0010
closest p · 0.0× alpha
0.0010
boldest claim

The sentences

highly significantP < 0.001actually significant
After excluding outliers exceeding 3 standard deviations (14 T1DM samples with S1P > 2315.3 nmol/L and 9 HC samples with S1P > 761.8 nmol/L), the difference remained highly significant (606.7 ± 431.8 vs. 390.8 ± 160.5 nmol/L, P < 0.001; Table 3 ), confirming that the elevation was not driven by extreme values.

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