Time-Course Transcriptomic Analysis Reveals PANoptosis-CCL2 Axis in Herpes Simplex Keratitis.

Invest Ophthalmol Vis Sci · 2026 · PMC13284957 · PMID 42312921

Europe PMC DOI

hedged sentences

—

closest p

—

boldest claim

The sentences

an increasing trendno p-value reported

In HSV-1–infected HCECs at 0, 6, 12, and 24 hpi, western blot analysis showed an increasing trend in the protein levels of PANoptosis-related molecules (GSDMD, MLKL, CASP3, RIPK3, CASP1, PARP) and their active forms, although p-MLKL and c-CASP3 showed a transient, non-significant decrease at 12 hpi ( Figs. 4 A, 4 B).

also in 63,971 other papers

a decreasing trendno p-value reported

Western blot results showed a significant increase in ZBP1 protein levels over the course of infection, whereas ASC protein levels displayed a decreasing trend ( Fig. 3 B).

also in 47,180 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.