KOLF2.1J iTF-Microglia: A standardized platform to study microglial transcriptional regulatory networks in CNS disease.

iScience · 2026 · PMC13285636 · PMID 42338472

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an overall trendno p-value reported

Within these differentially expressed genes, an overall trend observed was that homeostatic genes were downregulated while immune response genes were significantly upregulated, such as CXCL9 (Log 2 FC = 13.42, adj. p value = 0.04) and CXCL10 (Log 2 FC = 11.93, adj. p value = 4.43 × 10 −10 ; involved in immune cell recruitment and neuroinflammation); STAT1 (Lo

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