These included pathways central to adaptive immunity and autoimmunity—such as “Allograft rejection”, “Graft-versus-host disease”, and “Autoimmune thyroid disease”—as well as those governing immune cell trafficking and intercellular communication, exemplified by the highly significant enrichment of “Cytokine-cytokine receptor interaction” (adjusted P-values ranging from 0.001 to 0.004).
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LPIN3 emerges as a diagnostic biomarker in Moyamoya disease revealing immune-lipid metabolic crosstalk.
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