Increased uptake of specific metabolic substrates during cardiac resynchronization therapy despite no change in arterial concentrations: the very definition of metabolic flexibility.

The more precise lipidomic analysis of long chain FA uptake for example (Figure 3D) contains 363 measurements and is highly significant ( P < .001) as is the correlation with long-term reverse remodelling ( n = 231, from seven patients, P < .001, Supplementary Table 3).

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