Chemogenetic activation of cholinergic intrinsic cardiac ganglia improves border zone oxygenation and reduces arrhythmias during acute local ischemia.

Front Cardiovasc Med · 2026 · PMC13286828 · PMID 42344354

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an increasing trendno p-value reported

After administering CNO, NADH oxidation had an increasing trend in hearts from DREADDs-expressing rats compared to hearts without DREADDs, measured as a percent decrease in fNADH ( Figures 6B,C ).

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