Neuroimmune Correlates of HIV and Marijuana Use: Peripheral Biomarkers and Cognitive Function.

While clinical studies examining the effects of marijuana use on immune function remain limited and nuanced, population-based studies have reported no or marginally significant differences in pro-inflammatory markers such as C-reactive protein (CRP) and IL-6, while others have associated marijuana use with higher levels of anti-inflammatory cytokines (e.g., IL-20), lower levels of pro-inflammatory cytokines (e.g., IL-16), and decreased microbial translocation (Alshaarawy et al. 2019 ; Ellis et al. 2020 ; Krsak et al. 2021 ; Okafor et al. 2024 ).

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