Polygenic Risk Scores for Incident Dementia in the Multi-Ethnic Study of Atherosclerosis.

Genet Epidemiol · 2026 · PMC13288446 · PMID 42334086

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highly significantno p-value reported

For now, it seems there is no tradeoff between simplicity and accuracy; a simple C+T approach with only the most highly significant SNPs offers comparable prediction of dementia in populations with diverse ancestry.

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