Barely Significant
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Genetic-epigenetic interactions (meQTLs) in orofacial clefts etiology.

Mol Genet Genomics · 2026 · PMC13290791 · PMID 42334621

2
hedged sentences
0.0000
closest p · 0.0× alpha
0.0528
boldest claim

The sentences

highly significantP = 9.63 × 10 − 6actually significant
Most remarkably, rs987525 (8q24) demonstrated a highly significant association with cg16561172 ( MYC ) at P = 9.63 × 10 − 6 , representing the strongest statistical signal in our entire validation analysis.

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borderline significanceP = 5.28 × 10 − 2so close (0.05 < p ≤ 0.1)
The cg19191560 ( LGR4 ) site showed borderline significance in the combined analysis of 340 pairs ( P = 5.28 × 10 − 2 ), with similar trends observed in blood-specific analysis of 158 pairs ( P = 0.059) but not in saliva-specific analysis of 182 pairs ( P = 2.59 × 10 − 1 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.