Barely Significant
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Frailty index and type 2 diabetes with renal complications: insights from Mendelian randomization and retrospective observational study.

Ren Fail · 2026 · PMC13292309 · PMID 42336394

Europe PMCDOI
1
hedged sentence
0.0470
closest p · 0.9× alpha
0.0470
boldest claim

The sentences

borderline significancep = 0.047actually significant
Consistent results were obtained from maximum likelihood (OR: 5.63, 95% CI: 1.96–16.17, p = 0.001), weighted median (OR: 7.24, 95% CI: 1.83–28.73, p = 0.005), penalized weighted median (OR: 7.24, 95% CI: 1.86–28.14, p = 0.004), and IVW radial regression (OR: 5.31, 95% CI: 2.19–12.85, p = 0.001), while the weighted mode method yielded a directionally similar effect with borderline significance (OR: 9.10, 95% CI: 1.26–65.59, p = 0.047).

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