an increasing trendP > 0.05
Compared with the ACS group, the relative abundance of Firmicutes was significantly increased and that of Proteobacteria was significantly decreased in the SNDO group at d 24 and d 29 ( P < 0.05); in the SND group, the relative abundance of Firmicutes showed an increasing trend without statistical significance at d 29 ( P > 0.05), while the relative abundance of Proteobacteria was significantly decreased ( P < 0.05); the relative abundance of Firmicutes was significantly increased and that of Proteobacteria was significantly decreased at d 24 ( P < 0.05)( Fig. 5 C-D, J-K).