Barely Significant
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Genus- and host-associated codon usage bias patterns in coronavirus spike genes.

PLoS One · 2026 · PMC13293466 · PMID 42340955

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The sentences

highly significantp < 3.7 × 10 −11actually significant
A highly significant difference was observed for CAI ( p < 3.7 × 10 −11 ), indicating substantial host-associated variation in codon adaptation.

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