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The LAV-BPIFB4-Platelet-CD47 Axis: A Novel Mechanism Associated With Immune Resilience in Longevity.

Aging Cell · 2026 · PMC13295143 · PMID 42345378

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highly significantno p-value reported
We observed a highly significant percentage of CD47 + Thiazole Orange+ (TO + ) reticulated platelets (RPs)‐ newly released from the bone marrow‐ in LLIs compared to other age categories (1.41% ± 0.40% in > 95 vs. 0.38% ± 0.12% in 40–70 and 0.34% ± 0.14% in 20–39 year‐olds) (Figure 1A ) Interestingly, in young carriers (median‐age

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