a nonsignificant trendP = 0.072
RESULTS LPS Increases Microglial Proinflammatory Gene Expression LPS significantly increased microglial proinflammatory gene expression in C3-C6 spinal segments 24 h after administration: IL6 (4.3-fold; P = 0.005), CD14 (7.7-fold; P < 0.001), and Ptgs2 (2.4-fold; P = 0.021); there was a nonsignificant trend toward increased IL1β (3-fold, P = 0.072; Fig. 2 ).