Barely Significant
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Longitudinal Trends of Salivary Oxidized Thymosin β4 and β10 in Preterm Infants with Bronchopulmonary Dysplasia

Children (Basel) · 2026 · PMC13296937

2
hedged sentences
0.0010
closest p · 0.0× alpha
0.0560
boldest claim

The sentences

highly significantp < 0.001actually significant
In neonates without BPD, oxidized Tβ10 increased on average by 0.526 log units per week (95% CI: 0.303–0.750; p < 0.001), whereas in neonates with BPD, the variation was not significant (−0.073 log units/week; 95% CI: −0.209 to 0.064; p = 0.296); Percentage of oxidized Tβ10 : the BPD × Week interaction was highly significant (Wald χ 2 = 112.609; df = 2; p < 0.001).

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an increasing trendp = 0.056so close (0.05 < p ≤ 0.1)
In neonates without BPD, an increasing trend over time was observed (β = +0.247 log units/week; 95% CI: −0.006 to 0.500; p = 0.056), whereas in neonates with BPD, a significant reduction was observed (β = −0.161 log units/week; 95% CI: −0.307 to −0.014; p = 0.032); Percentage of oxidized Tβ4 : no significant difference was observed in the temporal trend of the percentage of oxidized Tβ4 between groups (BPD × time interaction: Wald χ 2 = 1.161; p = 0.560), suggesting that the relative oxidized fraction of the protein remains stable despite changes in absolute levels.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.