A cell atlas of the developing human outflow tract of the heart and its adult aortic valve derivatives.

We found that adult clusters 1, 4, and 7 retain expression of a highly significant fraction of distinctive embryonic genes, with clusters 4 and 7 largely maintaining embryonic cluster 4 expression signature (blue) ( Figure 5F, G ), while cluster 1 displays a significant match with embryonic cluster 20 (red) ( Figure 5F–H ).

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