Barely Significant
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Efficacy of Selenium Supplementation in Graves’ Orbitopathy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials with Trial Sequential Analysis

J Clin Med · 2026 · PMC13302020

2
hedged sentences
0.0500
closest p · 1.0× alpha
0.0500
boldest claim

The sentences

borderline significantp = 0.05actually significant
The test for subgroup differences was borderline significant ( p = 0.05), suggesting that treatment effects may vary according to disease severity ( Figure S9 ).

also in 7,848 other papers

a possible trendno p-value reported
Subgroup differences were not statistically significant ( p = 0.07), although a possible trend by disease severity was observed ( Figure S12 ). 3.4.

also in 1,026 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.