Barely Significant
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Elimination of tau tangles and soluble aggregates with the small molecule ACI-16664 prevents neurodegeneration in vivo.

Alzheimers Dement · 2026 · PMC13309853 · PMID 42363714

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hedged sentence
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closest p · 0.0× alpha
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highly significantp < 0.001actually significant
In contrast, Tg4510 mice treated with ACI‐16664 showed a highly significant ( p < 0.001) 51% reduction in aggregated hTau levels compared to vehicle‐treated controls.

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