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PEPITEM Regulates the Synovial Microenvironment During Immune-Mediated Inflammatory Arthritis to Limit Disease.

Arthritis Rheumatol · 2026 · PMC13313099 · PMID 41968960

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borderline significantno p-value reported
Of note, in depth analysis revealed less JE (CCL2), RANTES, IL‐16, and TREM‐1 proteins detected in mice treated with PEPITEM than in the control group, albeit TREM‐1 levels were borderline significant (Figure 5E–G , Supplementary Figure 7 ).

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