Barely Significant
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Longitudinal multiorgan transcriptomic atlas of salt-induced hypertension.

JCI Insight · 2026 · PMC13313555 · PMID 42024450

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highly significantP < 0.0001actually significant
These overlaps represented highly significant enrichments (Fisher’s exact test, P < 0.0001; odds ratios = 2.4 for hypertension and 3.8 for CKD), highlighting that the transcriptional shifts seen in our rat model overlap strongly with known human hypertension and CKD risk loci-associated genes.

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