Evaluating the efficacy and safety of nivolumab and ipilimumab combination therapy compared to nivolumab monotherapy in advanced cancers (excluding melanoma): a systemic review and meta-analysis.

J Egypt Natl Canc Inst · 2024 · PMC13313857 · PMID 38705953

Europe PMC DOI

hedged sentence

0.0400

closest p · 0.8× alpha

0.0400

boldest claim

The sentences

marginally significantp = 0.04actually significant

While this statistically significant result suggests a potential benefit in slowing disease progression, the small effect size and marginally significant p -value ( p = 0.04) underscore the need for cautious interpretation.

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