The marginally significant differences in the age and sex distributions are also supportive of the sufficient alignment of cohorts and the reduction of possible demographic confounding, which support the argument that the observed biochemical changes can be explained primarily by inflammatory processes caused by diseases as opposed to inherent properties of the initial population (García-Donas et al. , 2022; Allen et al. , 2023 ).
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Role of inflammatory cytokines in tissue remodeling and disease progression.
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