DNA-damage-targeting copper nanoparticles induce cuproptosis for enhanced cancer radiotherapy.

Mater Today Bio · 2026 · PMC13316202 · PMID 42382724

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a decreasing trendno p-value reported

The results showed that the mRNA levels of NSF1, ISCU, FXN, NFU1 and ACO2 all had a decreasing trend after adding Cu-MOF@ELS, indicating that Fe-S cluster synthesis was inhibited, which is consistent with the results of enzyme activity detection experiments.

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