Delaying surgery beyond six weeks after systemic therapy reduces postoperative morbidity without evidence of impaired oncologic outcomes in colorectal liver metastases.

BMC Cancer · 2026 · PMC13317304 · PMID 42380904

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0.0690

closest p · 1.4× alpha

0.0690

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The sentences

a nonsignificant trendP = 0.069so close (0.05 < p ≤ 0.1)

In univariable Cox regression using dichotomized TTS, a delay of ≥ 42 days showed a nonsignificant trend for liver-specific RFS (HR 0.688; 95% CI 0.460–1.030; P = 0.069; Table 4 A).

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