HNF4α controls growth, identity, and KRAS inhibitor response in invasive mucinous adenocarcinoma of the lung.

J Clin Invest · 2026 · PMC13318121 · PMID 42118585

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hedged sentence

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highly significantP < 1 × 10 –15actually significant

The 737 shared downregulated genes were enriched in GI pathways ( Figure 3E ), and this overlap was highly significant by hypergeometric test ( P < 1 × 10 –15 ; ~5-fold enrichment) ( 65 ).

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