Glucose and Glutamine Define Independent Activation-Braking Metabolic States in Triple Negative Breast Cancer Cells.

Cancer Genomics Proteomics · 2026 · PMC13321709 · PMID 42373230

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Functional enrichment of the glucose-exclusive upregulated DEG gene set (g:Profiler; Figure 5 ), data show a comprehensive and highly significant restoration of nuclear “execution” pathways, with selective re-engagement of the machinery for cell cycle, chromatin organization, DNA replication, DNA repair, centrosome organization, microtubule cytoskeleton organization, and mitotic spindle function.

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