Exercise and nutritional prehabilitation in gastrointestinal cancer patients: prospective controlled trial assessing feasibility, safety and effects on quality of life.

In the present study, exploratory survival analyses suggested a possible trend toward improved PFS and OS in the prehabilitation group; however, these findings must be interpreted with caution: The study was neither designed nor powered to detect survival differences, and the low number of events (four among 34 patients) introduces substantial statistical uncertainty and wide confidence intervals.

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Significance was set at p < 0.05, with p < 0.001 considered highly significant.

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