highly significantp < 0.001
The trend toward lower 28-day mortality at a higher Cr/CysC ratio was highly significant ( p < 0.001) ( Table 1 ). 3.2 Association between Cr/CysC ratio and 28-day mortality After performing univariate Cox regression analyses ( Supplementary Table S4 ), we constructed six multivariable Cox regression models to assess the relationship between the Cr/CysC ratio and 28-day mortality risk in patients with sepsis.