FAM134B-mediated ER-phagy degrades APP and suppresses Alzheimer's disease pathology.

EMBO J · 2026 · PMC13324857 · PMID 42192129

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We observed that UPR-related genes, across all three major UPR pathways, were upregulated at both the transcriptional and protein levels in 5XFAD mice, with an increasing trend as the mice aged (Fig.

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