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Guiding point-of-care therapeutic drug monitoring through structure-toxicity principles.

Chem Sci · 2026 · PMC13325025 · PMID 42394794

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a decreasing trendno p-value reported
3D shows that PHE, BUF and MET together form a decreasing trend from high log P , high affinity to low log P , low affinity, demonstrating that the mAb obtained in this study has an affinity gradient that matches the toxicity of the analyte.

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