Barely Significant
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Primary Tumor Resection in Patients With Unresectable Metastatic Colorectal Cancer: A Systematic Review and Meta-Analysis.

Ann Gastroenterol Surg · 2026 · PMC13327043 · PMID 42395138

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a favorable trendno p-value reported
Among them, only three concluded that PTR did not confer an OS benefit [ 41 , 53 , 55 ], whereas 11 reported a significant OS advantage associated with PTR [ 40 , 43 , 44 , 45 , 46 , 47 , 48 , 49 , 50 , 51 , 52 ], and the remaining two suggested a favorable trend [ 42 , 54 ].

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