Differential CpG methylation in the <i>Interferon Gamma</i> (<i>IFNG</i>) promoter correlates with viral load and transcriptional control in people with HIV.

Epigenetics · 2026 · PMC13327351 · PMID 42378170

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Results showed a highly significant positive correlation between average promoter CpG methylation and IFNG RT-qPCR ΔCt (Spearman R = 0.67, p < 0.0001, Figure 2C ), demonstrating increased IFNG promoter methylation is associated with decreased IFNG RNA expression.

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Differential CpG methylation in the &lt;i&gt;Interferon Gamma&lt;/i&gt; (&lt;i&gt;IFNG&lt;/i&gt;) promoter correlates with viral load and transcriptional control in people with HIV.

The sentences

Differential CpG methylation in the <i>Interferon Gamma</i> (<i>IFNG</i>) promoter correlates with viral load and transcriptional control in people with HIV.