Potential role of bile acids as a microbiome-derived mechanism in synovitis of knee osteoarthritis synovitis.

Osteoarthritis Cartilage · 2026 · PMC13327719 · PMID 41763351

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0.0550

closest p · 1.1× alpha

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boldest claim

The sentences

a positive trendp = 0.055so close (0.05 < p ≤ 0.1)

WOMAC components showed a positive trend-level correlation between lithocholic acid (feature 3782; rho= 0.380, p = 0.055, [95% CI: −0.001–0.41]) and candidate dehydroxylated BA(feature 4032; rho= 0.350, p = 0.080, [95% CI: −0.154–0.698]) with WOMAC stiffness, and between glycine dehydroxylated candidate (feature 3199) and WOMAC pain (rho= 0.376, p = 0.058, [95% CI: 0.003–0.669]).

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