Barely Significant
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Transporter gene variants influencing metformin pharmacokinetics and pharmacodynamics common in European populations: a pharmacogenetic narrative review.

Front Pharmacol · 2026 · PMC13328363 · PMID 42403712

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highly significantno p-value reported
detected highly significant improvement in metformin efficacy for homozygote AA compared to the AG as well as GG genotype carriers ( Imangaliyeva et al., 2025 ).

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