A QbD-based method for the simultaneous determination of tadalafil, terazosin, and tamsulosin using organic-solvent free mixed-micellar HPLC: a sustainable green approach.

BMC Chem · 2026 · PMC13330497 · PMID 42387558

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closest p · 0.0× alpha

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highly significantp < 0.0001actually significant

ANOVA results indicated that all proposed models were highly significant ( p < 0.0001), whereas lack-of-fit tests were not significant ( p > 0.05), suggesting a strong alignment between the experimental and predicted values.

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