Metabolic inhibition of glutamate-cysteine ligase increases dendritic cell-mediated antitumor immunity in melanoma.

J Immunother Cancer · 2026 · PMC13331211 · PMID 42379703

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highly significantno p-value reported

A p value of <0.05 was considered statistically significant (*), <0.01 very significant (**), <0.001 highly significant (***) and<0.0001 extremely significant (****).

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an overall trendno p-value reported

The GO Biological Process glutamine metabolic processes gene set revealed a more variable expression with an overall trend toward upregulation during tumor progression ( online supplemental figure S2A ).

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