Proteomic Profiling of Optic Nerves From SMOX-Deficient Mice Identifies Regulators of Neuroinflammation and Axonal Damage in Optic Neuritis.

Pathway Network Analysis Reveals Coordinated Dysregulation of Structural and Immune Pathways Pathway enrichment analysis comparing WT EAE versus WT CON identified highly significant enrichment in cellular components, with cell–substrate junction and focal adhesion-associated pathways showing the highest enrichment scores ( Fig. 4 A).

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