Kuang 6 demonstrated that the combined expression levels of secretory frizzled-related protein 4 (SFRP4), C-X-C chemokine receptor 4 (CXCR4), and fibrinogen (FIB) exhibit a highly significant correlation with the Wagner classification of diabetic foot, providing a robust molecular basis for non-invasive assessment of disease severity.
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Advances and Challenges in the Comprehensive Management of Diabetic Foot: A Narrative Review from a General Practice Perspective.
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